  | Laboratory of Wolfgang Liedtke, M.D., Ph.D. |      | | |
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| Nicolas Cenac, Christophe Altier, Kevin Chapman, Wolfgang Liedtke, Gerald Zamponi and Nathalie Vergnolle: Transient Receptor Potential Vanilloid-4 Has a Major Role in Visceral Hypersensitivity Symptoms, GASTROENTEROLOGY 2008 | |
| Jinju Li, Andrew J. Ghio, Seung-Hyun Cho, Constance E. Brinckerhoff, Sidney A. Simon and Wolfgang Liedtke: Diesel Exhaust Particles Activate the Matrix-Metalloproteinase-1 Gene in Human Bronchial Epithelia in a β-Arrestin–Dependent Manner via Activation of RAS, Environmental Health Perspectives, volume 117, number 3, March 2009 | |
| Ivan M. Lorenzo, Wolfgang Liedtke, Michael J. Sanderson, and Miguel A. Valverde. TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells. PNAS, August 21, 2008 | |
| Jun Yin, Julia Hoffmann, Stephanie M. Kaestle, Nils Neye, Liming Wang, Joerg, Baeurle, Wolfgang Liedtke, Songwei Wu, Hermann Kuppe, Axel R. Pries and Wolfgang M. Kuebler: Negative-Feedback Loop Attenuates Hydrostatic Lung Edema via a cGMP-Dependent Regulation of Transient Receptor Potential Vanilloid 4, Circulation Research | |
| Liedtke, Wolfgang, Chapter 5, TRPV Ion Channels and Sensory Transduction of Osmotic and Mechanical Stimuli in Mammals. Chapter in Martinac, B., (editor), "Sensing with ion channels", Springer, 2008 | |
| Ming-Yuan Jian, Judy A. King, Abu-Bakr Al-Mehdi, Wolfgang Liedtke, and Mary I. Townsley: High Vascular Pressure–Induced Lung Injury Requires P450 Epoxygenase–Dependent Activation of TRPV4, Am J Respir Cell Mol Biol Vol 38. pp 386–392, 2008 | |
| Sidney A. Simon, Wolfgang Liedtke, How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways, J Clin Invest 2008, 118, pp. 2383-2386 | |
| Stuart M. Brierley, Amanda J. Page, Patrick A. Hughes, Birgit Adam, Tobias Liebregts, Nicole J. Cooper, Gerald Holtmann, Wolfgang Liedtke and L. Ashley Blackshaw, Selective Role for TRPV4 Ion Channels in Visceral Sensory Pathways, Gastroenterology 2008;134:2059–2069 | |
| Walter E. B. Sipe, Stuart M. Brierley, Christopher M. Martin, Benjamin D. Phillis, Francisco Bautista Cruz, Eileen F. Grady, Wolfgang Liedtke, David M. Cohen, Stephen Vanner, L. Ashley Blackshaw, and Nigel W. Bunnett, Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia, Am J Physiol Gastrointest Liver Physiol 294 G1288–G1298, 2008. | |
| Wolfgang Liedtke: Molecular Mechanisms of TRPV4-Mediated Neural Signaling, Ann. N.Y. Acad. Sci. 1144: 42–52 (2008). 2008 New York Academy of Sciences. doi: 10.1196/annals.1418.012 | |
| Kazutoshi Hamanaka, Ming-Yuan Jian, David S. Weber, Diego F. Alvarez, Mary I. Townsley, Abu B. Al-Mehdi, Judy A. King, Wolfgang Liedtke, and James C. Parker, TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs. Am J Physiol Lung Cell Mol Physiol 293: L923–L932, 2007 | |
| Liedtke W (2007) Role of TRPV ion channels in sensory transduction. Exp Physiol 92.3 pp 507–512 | |
| Liu L, Chen L, Liedtke, W, Simon SA (2007) Changes in osmolality sensitize the response to capsaicin in trigeminal sensory neurons. J Neurophysiol. 97:2001-2015. | |
| Thomas Gevaert, Joris Vriens, Andrei Segal, Wouter Everaerts, Tania Roskams, Karel Talavera, Grzegorz Owsianik, Wolfgang Liedtke, Dirk Daelemans, Ilse Dewachter, Fred Van Leuven, Thomas Voets, Dirk De Ridder and Bernd Nilius. Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding. Journal of Clinical Investigation, Volume 117, Number 11, November 2007 | |
| Veronika Hartmannsgruber., Willm-Thomas Heyken., Michael Kacik, Anuradha Kaistha, Ivica Grgic, Christian Harteneck, Wolfgang Liedtke, Joachim Hoyer1, Ralf Ko¨ hler. Arterial Response to Shear Stress Critically Depends on Endothelial TRPV4 Expression. PLoS ONE 2(9): e827. doi:10.1371/journal.pone.0000827 | |
| Alvarez DF, King JA, Weber D, Addison E, Liedtke W, Townsley M (2006) Transient receptor potential vanilloid 4–mediated disruption of the alveolar septal barrier: A novel mechanism of acute lung injury. Circ Res. 99:988-995. | |
| Grant AD, Cottrell GS, Amadesi S, Trevisani M, Nicoletti P, Materazzi S, Altier C, Cenac N, Zamponi GW, Bautista-Cruz F, Lopez CB, Joseph E, Levine JD, Liedtke W, Vanner S, Vergnolle N, Geppetti P, Bunnett NW (2006) Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia. J Phys e-pub 10.1113/jphysiol.2006.121111 | |
| Liedtke W (2006) TRPV channels' function in osmo- and mechanotransduction. Chapter, from: TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades. CRC Press-Taylor&Francis, Boca Raton FL; Editors Wolfgang Liedtke and Stefan Heller; 31 chapters; 467 pages. | |
| Liedtke W (2006) Transient receptor potential vanilloid channels functioning in transduction of osmotic stimuli. Journal of Endocrinology. 191: 515-523. | |
| Liu L, Yang TM, Liedtke W, Simon, SA (2006) Chronic IL-1{beta} signaling potentiates voltage dependent sodium currents in trigeminal nociceptive neurons. J Neurophysiol. 95: 1478 –1490. | |
| Liu X, Bandyopadhyay B, Nakamoto T, Singh B, Liedtke W, Melvin JE (2006) A role for AQP5 in activation of TRPV4 by hypotonicity. THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 281, NO. 22, pp. 15485–15495 | |
| Alessandri-Haber N, Joseph E, Dina OA, Liedtke W, Levine JD (2005) TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator. Pain, 118(1-2):70-9. | |
| Liedtke W (2005) TRPV4 as osmosensor: a transgenic approach. Pflugers Arch – Eur J Physiol (2005) 451: 176–180 | |
| Liedtke W (2005) TRPV4 plays an evolutionary conserved role in the transduction of osmotic and mechanical stimuli in live animals. J Physiol 567.1 pp 53–58 | |
| Liedtke W, Kim C (2005) Functionality of the TRPV subfamily of TRP ion channels: add mechano-TRP and osmo-TRP to the lexicon! Cell Mol Life Sci. 62 2985–3001 | |
| Liedtke W, Simon SA (2004) A possible role for TRPV4 receptors in asthma. Am J Physiol Lung 287:269-271 | |
| Liedtke W, Friedman JM (2003) Abnormal osmotic regulation in trpv4-/- mice. PNAS, 100, 13698-13703 | |
| Liedtke W, Tobin DM, Bargmann CI, Friedman JM (2003) Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in C. elegans. PNAS, 100, 14531-14536 | |
| Liedtke W, Choe Y, Marti-Renom MA, Bell AM, Denis CS, Sali A, Hudspeth AJ, Friedman JM, Heller S. (2000) Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell, 103, 525-535 | |
| Wolfgang Liedtke, Winfried Edelmann, Fung-Chow Chiu, Raju Kucherlapati, and Cedric S. Raine: Experimental Autoimmune Encephalomyelitis in Mice Lacking Glial Fibrillary Acidic Protein Is Characterized by a More Severe Clinical Course and an Infiltrative Central Nervous System Lesion, American Journal of Pathology, Vol. 152, No. 1, January 1998 | |
| Liedtke, W, Edelmann, W, Bieri PL, Chiu, F-C, Cowan NJ, Kucherlapati, R, Raine, CS (1996) GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination. Neuron 17:607-615 | |
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