Center for Translational Neuroscience / Faculty / McNamara

Laboratory of James O. McNamara, M.D.

	Huang, Y.Z., Pan, E., Xiong, Z.Q., and McNamara, J.O. Zinc-mediated transactivation of TrkB potentiates the hippocampal mossy fiber CA3 pyramid synapse. Neuron, 57:546-558, 2008
	Huang, Y.Z., Pan, E., Xiong, Z.Q., and McNamara, J.O. Zinc-mediated transactivation of TrkB potentiates the hippocampal mossy fiber CA3 pyramid synapse. Neuron, 57:546-558, 2008. Highlighted in a preview written by Bai Lu and colleagues.
	Bausch, S. B., He,S., Petrova, Y., Wang, X. M. and McNamara, J. O. (2006) Plasticity of both excitatory and inhibitory synapses is associated with seizures induced by removal of chronic blockade of activity in cultured hippocampus. Journal of Neurophysiology 96:2151-2167.
	Loo, L.S and McNamara, J.O. (2006) Impaired volume regulation is the mechanism of excitotoxic sensitization to complement. Journal of Neuroscience 26:10177-10187.
	McNamara, J.O., Huang, Y.Z., and Leonard, A.S. (2006) Molecular signaling mechanisms underlying epileptogenesis. Science's STKE 10 October 2006: re12.
	Puranam, R. S., Jain, S., Kleindienst, A. M., Saxena, S., Kim, M. K., Changizi, B. K., Padma, M. V., Andrews, I., Elston, R. C., Tiwari, H. K., and McNamara, J. O. (2005) A locus for generalized tonic-clonic seizure susceptibility maps to chromosome 10q25-q26. Annals of Neurology 58(3):449-458.
	Danzer S.C., Pan E., Nef S., Parada L.F., and McNamara J.O. (2004) Altered regulation of brain-derived neurotrophic factor protein in hippocampus following slice preparation. Neuroscience 126:859-869.
	He X.-P., Kotloski R., Nef S., Luikart B.W., Parada L.F., and McNamara J.O. (2004) Conditional Deletion of TrkB but Not BDNF Prevents Epileptogenesis in the Kindling Model. Neuron 43:31-42.
	Xiong Z.Q., Qian W., Suzuki K., and McNamara J.O. (2003) Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration. J Neurosci 23: 955-960.
	He X.P., Minichiello L., Klein R. and McNamara J.O. (2002) Immunohistochemical evidence of seizure-induced activation of trkB receptors in the mossy fiber pathway of adult mouse hippocampus. J. Neurosci., 22:7502-7508.
	Xiong Z.Q. and McNamara J.O. (2002) Fleeting activation of ionotropic glutamate receptors sensitizes cortical neurons to complement attach. Neuron 36:363-374.
	Yang R, Puranam RS, Butler LS, Qian WH, He XP, Moyer MB, Blackburn K, Andrews PI and McNamara JO (2000) Autoimmunity to Munc-18 in Rasmussen’s encephalitis. Neuron 28:375-383.
	Binder DK, Routbort MJ and McNamara JO (1999) Seizures activate trk receptors in the mossy fiber pathway of adult rat hippocampus. J Neurosci 19:4616-4626.
	Whitney KD, Andrews PI and McNamara JO (1999) Immunoglobulin G and complement immunoreactivity in the cerebral cortex of Rasmussen’s encephalitis patients. Neurology 53:699-708.
	Janumpalli S, Butler LS, MacMillan LB, Limbird LE and McNamara JO (1998) A point mutation (D79N) of the α2A adrenergic receptor abolishes the anitepileptogenic action of endogenous norepinephrine. J Neurosci, 18:2004-2008.
	Sprengel R, Suchanek B, Amico C, Brusa R, Burnashev N, Rosov A, Hvalby O, Jensen V, Paulsen O, Andersen P, Kim JJ, Thompson RF, Sun W, Webster LC, Grant SGN, Eilers J, Konnerth A, Li J, McNamara JO and Seeburg PH (1998) Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo. Cell 92:279-289.