Ontogeny of Seizure-Induced Increases in BDNF Immunoreactivity and TrkB Receptor Activation in Rat Hippocampus

Transmission confocal microscopy image of BDNF immunohistochemistry (red) and phospho-Trk immunohistochemistry (green) in the hippocampus of a 22-day-old rat 24 hours after kainate-induced status epilepticus. Images of BDNF and phospho-Trk immunohistochemistry were taken from adjacent sections from the same animal and superimposed. Colocalization of BDNF and phospho-Trk immunoreactivity is shown in the mossy fiber pathway.