The study of neuronal calcium-regulated transcription factors

CaRF is a novel calcium-regulated transcription factor that modulates transcription of the gene for Brain-derived neurotrophic factor (BDNF). CaRF (labeled in red) is a nuclear protein (DNA is labeled with Hoechst dye in blue) in cultured cortical neurons (labeled for the neuron-specific protein β-tubulin III in green). Tao, X (2002), Neuron 33:383.