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The Neurotransgenic Laboratory (NTL) at Duke University conducts technology development research and provides services towards the genetic analysis of the nervous system.
The nervous system with its vast diversity of cell types and synaptic connections requires sophisticated tools to visualize and modify neuronal activity and interactions. Genetically engineered animal models allow such precise modifications. The Neurotransgenic Laboratory is focused on the application of genetically-altered animal models in neuroscience research. The NTL offers coordinated expertise in the generation of genetically modified animals "from concept through creation" and supports state-of-the-art facilities and services to provide an enriched environment for students, trainees, and established investigators utilizing genetically altered animals in research.
Research, teaching, and service components of the NTL include experimental project design and planning, molecular construct preparation, microinjection, and other areas. Ultimately, the mission of the NTL is to develop, promote, and enhance genetically modified animal model systems for understanding and resolving biomedical problems in basic and translational neuroscience research.