Dong Yan

Assistant Professor of Molecular Genetics and Microbiology
Assistant Professor of Neurobiology
Faculty Network Member of the Duke Institute for Brain Sciences
Affiliate of the Duke Regeneration Center
Email address:

I am interested in understanding the molecular mechanisms underlying neural circuit formation during development and degeneration in aging. In my lab, We use a free-living tiny roundworm, called Caenorhabditis elegans, as a model. The defined cell lineage, completely mapped connectome and rapid life cycle of this organism greatly facilitate investigating nervous system at the subcellular resolution. Combining classic genetic analysis with in vivo live imaging technique and molecular and cellular manipulations, we are discovering conserved mechanisms playing key roles in neural circuit formation, gap junction dynamics and neurodegeneration

Education and Training

  • Chinese Academy of Sciences, Shanghai Institute for Biological Sciences (China), Ph.D. 2006

Associated Faculty Labs

Department Affiliation

  • Department of Molecular Genetics and Microbiology