Marc Caron

Professor of Cell Biology
James B. Duke Professor of Cell Biology
Vice Chair for Science and Research in the Department of Cell Biology
Professor in Neurobiology
Professor in Medicine
Faculty Network Member of the Duke Institute for Brain Sciences
Member of the Duke Cancer Institute
Affiliate of the Regeneration Next Initiative
Campus mail: CARL Building Room 487, Durham, NC 27710
Phone: (919) 684-5433
Email address: marc.caron@duke.edu

Studies of the mechanisms of action and regulation of hormones and neurotransmitters at the cellular and molecular levels constitute the main goals our of research activities. G protein-coupled receptors (GPCR) mediate the actions of signaling molecules from unicellular organisms to man. We have used adrenergic and dopamine receptors to characterize the structure/function and regulation mechanisms of these prototypes of G protein-coupled receptors. Another approach has been to characterize the nature of neurotransmitter transporters for dopamine, serotonin and other neurotransmitters in an attempt to understand their function in normal and pathological neurotransmission. Another goal of our laboratory is to define the genes and pathways involved in the reinforcing properties of drugs of abuse using both forward and reverse genetic approaches. Our laboratory uses biochemical, molecular biology and gene targeting approaches to examine these questions.

Education and Training

  • University of Miami, Ph.D. 1973

Associated Faculty Labs

Selected Grants and Awards

Department Affiliation

  • Department of Cell Biology

Publications

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