Luping Yin

Phone: (919) 684-6091
Email address:

Education & Training

July 2016 - March 2017: Research assistant in Beijing Normal University, China (PI: Yousheng Shu).
Sept. 2011 - April 2016: Ph.D in Laboratory of Neural Network Function, Institute of Neuroscience, CAS, China (PI: Yousheng Shu).
Sept. 2007 - July 2011: Bachelor in College of Life Sciences, Lanzhou University, China.

Research interests

It is known that general anesthesia induces the loss-of-conscious brain state. I am interested in dissecting the critical circuits that mediate the effects of general anesthesia.

Associated labs, publications, & achievements


  1. Tan, G.-H., Y.-Y. Liu, L. Wang, K. Li, Z.-Q.,…, Yin, L., …, Z.-Y. Wu and Z.-Q. Xiong. "PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum." Cell Res. doi: 10.1038/cr.2017.128 (2017)
  2. Wang, B., Ke, W., Guang, J., Chen, G., Yin, L., Deng, S., He, Q., Liu, Y., He, T., Zheng, R., Jiang, Y., Zhang, X., Li, T., Luan, G., Lu, H. D., Zhang, M., Zhang, X., Shu, Y. Firing Frequency Maxima of Fast-Spiking Neurons in Human, Monkey, and Mouse Neocortex. Frontiers in cellular neuroscience 10, 239, doi:10.3389/fncel.2016.00239 (2016).
  3. Yin, L., Rasch, M. J., He, Q., Wu, S., Dou, F., Shu, Y. Selective Modulation of Axonal Sodium Channel Subtypes by 5-HT1A Receptor in Cortical Pyramidal Neuron. Cerebral cortex (New York, N.Y. : 1991), doi:10.1093/cercor/bhv245 (2015).
  4. Wang, T., Yin, L., Zou, X., Shu, Y., Rasch, M. J., Wu, S. A Phenomenological Synapse Model for Asynchronous Neurotransmitter Release. Frontiers in computational neuroscience 9, 153, doi:10.3389/fncom.2015.00153 (2015).
  5. Wang, B., Yin, L., Zou, X., Ye, M., Liu, Y., He, T., Deng, S., Jiang, Y., Zheng, R., Wang, Y., Yang, M., Lu, H., Wu, S., Shu, Y. A Subtype of Inhibitory Interneuron with Intrinsic Persistent Activity in Human and Monkey Neocortex. Cell Rep 10, 1450-1458, doi:10.1016/j.celrep.2015.02.018 (2015).
  6. Jiang, M., Yang, M., Yin, L., Zhang, X. & Shu, Y. Developmental reduction of asynchronous GABA release from neocortical fast-spiking neurons. Cerebral cortex (New York, N.Y. : 1991) 25, 258-270, doi:10.1093/cercor/bht236 (2015).

Awards & Honors

  1. 2007-2011 Hong Kong Siyuan Financial Support
  2. 2011 Excellent thesis and graduate
  3. 2016 Di-Ao scholarship (grade 1) and Reward-Basic medicine scholarship (grade 1)
  4. 2017 Duke Neurobiology fall retreat program: best postdoctoral poster.