Caron Publications

Slosky, Lauren M., Marc G. Caron, and Lawrence S. Barak. “Biased Allosteric Modulators: New Frontiers in GPCR Drug Discovery.” Trends Pharmacol Sci 42, no. 4 (April 2021): 283–99.
Smith, Jeffrey S., Thomas F. Pack, Asuka Inoue, Claudia Lee, Kevin Zheng, Issac Choi, Dylan S. Eiger, et al. “Noncanonical scaffolding of Gαi and β-arrestin by G protein-coupled receptors.” Science 371, no. 6534 (March 12, 2021).
Favier, Mathieu, Helena Janickova, Damian Justo, Ornela Kljakic, Léonie Runtz, Joman Y. Natsheh, Tharick A. Pascoal, et al. “Cholinergic dysfunction in the dorsal striatum promotes habit formation and maladaptive eating.” J Clin Invest 130, no. 12 (December 1, 2020): 6616–30.
Porter-Stransky, Kirsten A., Alyssa K. Petko, Saumya L. Karne, L Cameron Liles, Nikhil M. Urs, Marc G. Caron, Carlos A. Paladini, and David Weinshenker. “Loss of β-arrestin2 in D2 cells alters neuronal excitability in the nucleus accumbens and behavioral responses to psychostimulants and opioids.” Addict Biol 25, no. 6 (November 2020): e12823.
Slosky, Lauren M., Yushi Bai, Krisztian Toth, Caroline Ray, Lauren K. Rochelle, Alexandra Badea, Rahul Chandrasekhar, et al. “β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors.” Cell 181, no. 6 (June 11, 2020): 1364-1379.e14.
Li, Yan-Chun, Priyalakshmi Panikker, Bo Xing, Sha-Sha Yang, Cassandra Alexandropoulos, Erin P. McEachern, Rita Akumuo, et al. “Deletion of Glycogen Synthase Kinase-3β in D2 Receptor-Positive Neurons Ameliorates Cognitive Impairment via NMDA Receptor-Dependent Synaptic Plasticity.” Biol Psychiatry 87, no. 8 (April 15, 2020): 745–55.
Boone, Peter G., Lauren K. Rochelle, Joshua D. Ginzel, Veronica Lubkov, Wendy L. Roberts, P. J. Nicholls, Cheryl Bock, et al. “A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion.” Nat Commun 10, no. 1 (December 2, 2019): 5490.
Jacobsen, Jacob P. R., Adrianna Oh, Rachel Bangle, Wendy L. Roberts, Elizabeth L. Royer, Nathan Modesto, Sonora A. Windermere, et al. “Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept.” Neuropsychopharmacology 44, no. 12 (November 2019): 2082–90.
Martini, Michael L., Caroline Ray, Xufen Yu, Jing Liu, Vladimir M. Pogorelov, William C. Wetsel, Xi-Ping Huang, John D. McCorvy, Marc G. Caron, and Jian Jin. “Designing Functionally Selective Noncatechol Dopamine D1 Receptor Agonists with Potent In Vivo Antiparkinsonian Activity.” Acs Chem Neurosci 10, no. 9 (September 18, 2019): 4160–82.