Franks Lab Publications

Olfactory Circuits

Complementary codes for odor identity and odor intensity in olfactory cortex.
Bolding KA & Franks KM. (2017) eLife 10.7554/eLife.22630.

Odor identity coding by distributed ensembles of neurons in the mouse olfactory cortex.
Roland B, Deneux T, Franks KM, Bathellier B, Fleischmann A. (2017) eLife 10.7554/eLife.26337.

A transformation from temporal to ensemble coding in a model of piriform cortex.
Stern M, Bolding KA, Abbott LF & Franks KM. (2017) bioRxiv.

Massive normalization of olfactory bulb output in mice with a “monoclonal nose.”
Roland B, Jordan R, Sosulski DL, Diodato A, Fukunaga I, Wickersham I, Franks KM, Schaefer AT & Fleischmann A.  (2016)  eLife 10:7554/eLife.16335.

I Want It All and I Want It Now: How a Neural Circuit Encodes Odor with Speed and Accuracy.
Franks KM. (2015)  Neuron. 88: 852-4.

Multi-step signaling from sensory neurons onto olfactory bulb mitral cells. 
Gire DH*, Franks KM*, Zak JD, Tanaka KF, Whitesell JD, Mulligan AA, Hen R, Schoppa NE. (2012) J. Neurosci. 32: 2964-75.

Recurrent circuitry dynamically shapes the activation of piriform cortex.
Franks KM, Russo MJ, Sosulski DL, Mulligan AA, Siegelbaum SA, Axel, R. (2011) . Neuron. 72: 49-56.

Mice with a "monoclonal nose": perturbations in an olfactory map impair odor discrimination.
Fleischmann A, Shykind BM, Sosulski DL, Franks KM, Glinka ME, Mei DF, Sun Y, Kirkland J, Mendelsohn M, Albers MW, Axel R. (2008)  Neuron. 60: 1068-81.

Strong single-fiber sensory inputs to olfactory cortex: implications for olfactory coding
Franks KM, Isaacson JS. (2006) Neuron. 49: 357-363.

Synapse specific downregulation of NMDA receptors by early experience: a critical period for plasticity of sensory input to olfactory cortex
Franks KM, Isaacson JS. (2005) Neuron. 47: 101-114.

* denotes equal authorship

Technology Development

Single-cell genetic transfection via in vivo whole-cell recording: bridging physiology, genetics and connectomics.
Rancz EA*, Franks KM*, Schwartz, M Schaefer AT, Seeburg P, Margrie TW. (2011)  Nature Neuroscience. 14: 527-532.

Older Publications

NGF is essential for hippocampal plasticity and learning.
Conner JM*, Franks KM*, Titterness AK*, Russell K, Merrill DA, Christie BR, Sejnowski TJ, Tuszynski MH. (2009)  J. Neurosci. 29: 10883-10889.

Calmodulin activation by calcium transients in the postsynaptic density of dendritic spines
Keller DK, Franks KM, Bartol TM, Sejnowski TJ. (2008) PLoS One. 3: e2045.

Independent sources of synaptic variability at single glutamatergic synapses
Franks KM, Stevens CF, Sejnowski TJ. (2003) J. Neurosci. 23: 3186-3195.

Complexity of calcium signaling in synaptic spines.
Franks KM, Sejnowski TJ. (2002)  Bioessays. 24: 1130-1144.

A Monte Carlo model reveals independent signaling at central glutamatergic synapses
Franks KM*, Bartol TM*, Sejnowski, TJ. (2002) Biophys J. 83: 2333-2348.

An MCell model of calcium dynamics and frequency-dependence of calmodulin activation in dendritic spines
Franks KM, Bartol TM, Sejnowski TJ. (2001). Neurocomputing. 38-40: 9-16.

Synaptic plasticity in morphologically identified CA1 Stratum Radiatum interneurons and projection cells.
Christie BR, Franks KM, Seamans JK, Saga K, Sejnowski, TJ. (2000).  Hippocampus. 10: 678-683.

Bolding, Kevin A., and Kevin M. Franks. “Recurrent cortical circuits implement concentration-invariant odor coding..” Science 361, no. 6407 (September 14, 2018). https://doi.org/10.1126/science.aat6904.
Stern, Merav, Kevin A. Bolding, L. F. Abbott, and Kevin M. Franks. “A transformation from temporal to ensemble coding in a model of piriform cortex..” Elife 7 (March 29, 2018). https://doi.org/10.7554/eLife.34831.
Nagappan, Shivathmihai, and Kevin M. Franks. “Learning: Plasticity without Stabilization in Olfactory Cortex..” Curr Biol 28, no. 1 (January 8, 2018): R23–25. https://doi.org/10.1016/j.cub.2017.11.010.
Roland, Benjamin, Thomas Deneux, Kevin M. Franks, Brice Bathellier, and Alexander Fleischmann. “Odor identity coding by distributed ensembles of neurons in the mouse olfactory cortex..” Elife 6 (May 10, 2017). https://doi.org/10.7554/eLife.26337.
Bolding, Kevin A., and Kevin M. Franks. “Complementary codes for odor identity and intensity in olfactory cortex..” Elife 6 (April 5, 2017). https://doi.org/10.7554/eLife.22630.
Roland, Benjamin, Rebecca Jordan, Dara L. Sosulski, Assunta Diodato, Izumi Fukunaga, Ian Wickersham, Kevin M. Franks, Andreas T. Schaefer, and Alexander Fleischmann. “Massive normalization of olfactory bulb output in mice with a 'monoclonal nose'..” Elife 5 (May 13, 2016). https://doi.org/10.7554/eLife.16335.
Franks, Kevin M. “I Want It All and I Want It Now: How a Neural Circuit Encodes Odor with Speed and Accuracy..” Neuron 88, no. 5 (December 2, 2015): 852–54. https://doi.org/10.1016/j.neuron.2015.11.016.
Gire, David H., Kevin M. Franks, Joseph D. Zak, Kenji F. Tanaka, Jennifer D. Whitesell, Abigail A. Mulligan, René Hen, and Nathan E. Schoppa. “Mitral cells in the olfactory bulb are mainly excited through a multistep signaling path..” J Neurosci 32, no. 9 (February 29, 2012): 2964–75. https://doi.org/10.1523/JNEUROSCI.5580-11.2012.
Franks, Kevin M., Marco J. Russo, Dara L. Sosulski, Abigail A. Mulligan, Steven A. Siegelbaum, and Richard Axel. “Recurrent circuitry dynamically shapes the activation of piriform cortex..” Neuron 72, no. 1 (October 6, 2011): 49–56. https://doi.org/10.1016/j.neuron.2011.08.020.
Rancz, Ede A., Kevin M. Franks, Martin K. Schwarz, Bruno Pichler, Andreas T. Schaefer, and Troy W. Margrie. “Transfection via whole-cell recording in vivo: bridging single-cell physiology, genetics and connectomics..” Nat Neurosci 14, no. 4 (April 2011): 527–32. https://doi.org/10.1038/nn.2765.