H. Yang Publications

Liang, Pengfei, and Huanghe Yang. “Molecular underpinning of intracellular pH regulation on TMEM16F.” J Gen Physiol 153, no. 2 (February 1, 2021). https://doi.org/10.1085/jgp.202012704.
Le, Son C., and Huanghe Yang. “An Additional Ca2+ Binding Site Allosterically Controls TMEM16A Activation.” Cell Rep 33, no. 13 (December 29, 2020): 108570. https://doi.org/10.1016/j.celrep.2020.108570.
Liao, Chengheng, Yang Zhang, Cheng Fan, Laura E. Herring, Juan Liu, Jason W. Locasale, Mamoru Takada, et al. “Identification of BBOX1 as a Therapeutic Target in Triple-Negative Breast Cancer.” Cancer Discov 10, no. 11 (November 2020): 1706–21. https://doi.org/10.1158/2159-8290.CD-20-0288.
Zhang, Guohui, Rebecca A. Gibson, Marie McDonald, Pengfei Liang, Po Wei Kang, Jingyi Shi, Huanghe Yang, Jianmin Cui, and Mohamad A. Mikati. “A Gain-of-Function Mutation in KCNMA1 Causes Dystonia Spells Controlled With Stimulant Therapy.” Mov Disord 35, no. 10 (October 2020): 1868–73. https://doi.org/10.1002/mds.28138.
Le, Trieu, Son C. Le, Yang Zhang, Pengfei Liang, and Huanghe Yang. “Evidence that polyphenols do not inhibit the phospholipid scramblase TMEM16F.” J Biol Chem 295, no. 35 (August 28, 2020): 12537–44. https://doi.org/10.1074/jbc.AC120.014872.
Zhang, Yang, Trieu Le, Ryan Grabau, Zahra Mohseni, Hoejeong Kim, David R. Natale, Liping Feng, Hua Pan, and Huanghe Yang. “TMEM16F phospholipid scramblase mediates trophoblast fusion and placental development.” Sci Adv 6, no. 19 (May 2020): eaba0310. https://doi.org/10.1126/sciadv.aba0310.
Le, Son C., Zhiguang Jia, Jianhan Chen, and Huanghe Yang. “Molecular basis of PIP2-dependent regulation of the Ca2+-activated chloride channel TMEM16A.” Nat Commun 10, no. 1 (August 21, 2019): 3769. https://doi.org/10.1038/s41467-019-11784-8.
Le, Trieu, Zhiguang Jia, Son C. Le, Yang Zhang, Jianhan Chen, and Huanghe Yang. “An inner activation gate controls TMEM16F phospholipid scrambling.” Nat Commun 10, no. 1 (April 23, 2019): 1846. https://doi.org/10.1038/s41467-019-09778-7.
Le, Trieu, Son C. Le, and Huanghe Yang. “Drosophila Subdued is a moonlighting transmembrane protein 16 (TMEM16) that transports ions and phospholipids.” J Biol Chem 294, no. 12 (March 22, 2019): 4529–37. https://doi.org/10.1074/jbc.AC118.006530.