Research Roundup: April 2018

Tuesday, May 8, 2018
By Jennifer Kornbluth
neuron

Here are summaries of a selection of the papers published by Duke Neurobiology in April 2018:

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Yong-hui Jiang was part of a team that successfully generated the first shank3b −/− zebrafish model displaying robust autism-like behavioral and molecular characteristics using CRISPR/Cas9 gene editing approach. Read more

Hiroaki Matsunami and collaborators proposed elucidated how olfactory receptors are activated by musks, an important component of perfumes. Read more

Senses:

Valeria Caruso and team studied three visual-motor areas --  frontal eye fields, intraparietal cortex, and superior colliculus -- and found that only the superior colliculus provides a stable code for stimulus position in space that survives saccadic changes in eye position. Read more

Hiroaki Matsunami and collaborators proposed elucidated how olfactory receptors are activated by musks, an important component of perfumes. Read more

Neural cell biology:

Jeremy Kay and Greg Field's labs identified a mechanism that allows retinal neurons to establish neural connections and detect motion correctly. They postulate that similar mechanisms could operate in many neural circuits. Read more

Reviews:

Rich Mooney reviews a seminal paper published in 2000 by Michael Brainard and Allison Doupe showing that an active process in the cortex and basal ganglia leads to deterioration of birdsong  following deafening. Read more

Audrey Dickey and Al La Spada review current Huntington Disease strategies and explain how current advances in therapeutics for HD could change approaches and lead to disease-modifying therapies for many neurodegenerative diseases. Read more