Research Roundup: Spring 2019

Monday, June 10, 2019
By Jennifer Kornbluth
Nerve images

Here are summaries of a selection of the papers published by Duke Neurobiology in Spring 2019:

Movement:

  • Huanghe Yang and collaborators found that Subdued, a Drosophila transmembrane protein 16 (TMEM16) ortholog, harbors biophysical features that strikingly resemble those of the mammalian TMEM16F. The findings can provide new insights into understanding the evolution of TMEM16 family and the molecular mechanisms of their ion and phospholipid permeation. Read more: http://www.jbc.org/content/294/12/4529.long
  • Miguel Nicolelis and team developed a novel, non-invasive neurorehabilitation protocol for locomotion training for patients with severe chronic paraplegia resulting from spinal cord injuries. The protocol targets both musculoskeletal training and corticospinal plasticity. Read more: https://www.nature.com/articles/s41598-019-43041-9#Sec2

Memory:

  • Alex Vaz and Nicolas Brunel discover that just before the brain successfully retrieves a memory, “ripples” in the brain’s medial temporal lobe couple with similar oscillations in the temporal association cortex. Read more: https://science.sciencemag.org/content/363/6430/975.long

Neural Cell Biology:

Senses:

Social Interactions

  • Yong-hui Jiang was part of a team that successfully provided the first demonstration of how a genetically modified non-human primate can be used for translational research on therapeutics for autism spectrum disorder. Read more: https://academic.oup.com/hmg/article/28/4/561/5133462