The maturation of the frontal cortex occurs over adolescence and is accompanied by dramatic changes in behavior in mammalian species. This period of brain development is often viewed as a late sensitive period for learning and higher cognition and is also a moment of psychiatric vulnerability in humans. Our lab uses mouse models to access the cellular and synaptic aspects of frontal cortex maturation. I will review how cells and synapses and frontal cortex-relevant behaviors change through adolescence in mice and discuss the role of experience and pubertal hormones in these transitions.
October 16, 2018 - 12:00pm to 1:00pm
Linda Wilbrecht; hosted by Jeremy Kay