Memory engrams: remember the past and imagine the future

September 25, 2020 - 3:00pm to 4:00pm
Sheena Josselyn, PhD
Josselyn headshot

The ability to form memory is an essential trait that allows learning and the accumulation of knowledge. But what is a memory? There has been a long history of searching for the neuronal substrate that forms memory in the brain, and the emerging view is that ensembles of engram cells explain how memories are formed and retrieved. Josselyn will discuss the evidence for engram cells as a substrate of memory, particularly in rodents; what she has learned so far about the features of memory, including memory formation, retrieval over time, and loss; and future directions to understand how memory becomes knowledge.